COCVD RESEARCH CORES
The COCVD projects are facilitated by services provided through cutting-edge Research Cores. Cores within the COCVD include the Administrative Core A, Analytical Core B, Analytical Core B, Physiological Core C, and Pathology Core D. A description of each core, supervised by a core director, is provided below.
ADMINISTRATIVE CORE A
Director: Lisa Cassis, Ph.D.
Purpose: The administrative core facilitates and coordinates the research objectives of the COCVD.The core provides organization and administrative structure to ensure that investigators affiliated with the Center operate in an environment that facilitates their research. This includes access to biostatistical support from Dr. Richard Charnigo, Ph.D. and Dr. Katherine Thompson, Ph.D.
ANALYTICAL RESEARCH CORE B
Director: Andrew Morris, Ph.D.
Purpose: The Analytical Core provides technical services and support to Center participants in the broad area of detection and quantitation of biological molecules of relevance to the diagnosis, treatment and experimental investigation of obesity and cardiovascular diseases. This includes suspension array (Luminex), and electrospray ionization tandem mass spectrometry platforms for lipid and metabolite profiling.
PHYSIOLOGIC CORE C
Director: Lisa A. Cassis, Ph.D.
Purpose: The Physiologic Core provides the necessary equipment and technical expertise to perform critical physiologic measures that are essential to achieve the objectives of the COCVD. This includes quantification of (1) whole body metabolism, (2) diabetes, and (3) cardiovascular diseases (hypertension, atherosclerosis). These phenotypes are quantified using NMR, TSE LabMaster cages, TSE PhenoMaster cages, and imaging (ultrasound, MRI).
PATHOLOGY RESEARCH CORE D
Director: Wendy Katz, Ph.D.
Purpose: The Pathology Core provides the necessary equipment and technical expertise to perform histological analysis on tissues. The Core is equipped with tissue processors, microtomes, and microscopy/image analysis equipment for processing paraffin-embedded tissues and performing basic stains.